European equities traded in the US as American depositary receipts were tracking lower late Tuesday morning, declining 1.17% to 1,742.51 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by biotech firm Evaxion (EVAX) and pharmaceutical company Ascendis Pharma (ASND), which advanced 4.6% and 1.3%, respectively. They were followed by biopharmaceutical company DBV Technologies (DBVT) and oil and gas company TotalEnergies (TTE), which 1.8% and 1.3%, respectively.

The decliners from continental Europe were led by medical device maker EDAP TMS (EDAP) and semiconductor company Sequans Communications (SQNS), which shed 11.3% and 4.6%, respectively. They were followed by internet browser company Opera (OPRA) and accommodations booking site trivago (TRVG), which dropped 4.6% and 2.3%, respectively.

From the UK and Ireland, the gainers were led by biopharmaceutical company Bicycle Therapeutics (BCYC) and educational publisher Pearson (PSO), which increased 4% and 1.2% respectively. They were followed by lender Lloyds Banking Group (LYG) and telecommunications operator Vodafone Group (VOD), which were up 0.7% and 0.2% respectively.

The decliners from the UK and Ireland were led by biopharmaceutical company Mereo BioPharma Group (MREO) and pharmaceutical company AstraZeneca (AZN), which fell 8.2% and 4.3% respectively. They were followed by biopharmaceutical company NuCana (NCNA) and biotech firm Trinity Biotech (TRIB), which lost 3.3% and 1%, respectively.