Ardelyx Launches Phase 3 ACCEL Trial of IBSRELA for Chronic Idiopathic Constipation

Reuters

01/28

<a href="https://laohu8.com/S/ARDX">Ardelyx</a> Launches Phase 3 ACCEL Trial of IBSRELA for Chronic Idiopathic Constipation

Ardelyx Inc. has announced the dosing of the first patient in ACCEL, a Phase 3 clinical trial evaluating IBSRELA (tenapanor) for the treatment of chronic idiopathic constipation (CIC) in adults. The multicenter, randomized, double-blind, placebo-controlled study aims to enroll approximately 700 patients, assessing the safety and efficacy of tenapanor administered twice daily over 26 weeks. The primary endpoint will focus on patient-reported outcomes in constipation. Enrollment is expected to continue through 2026, with topline data anticipated in the second half of 2027. Results from the trial have not yet been presented.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ardelyx Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9644324-en) on January 28, 2026, and is solely responsible for the information contained therein.

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The multicenter, randomized, double-blind, placebo-controlled study aims to enroll approximately 700 patients, assessing the safety and efficacy of tenapanor administered twice daily over 26 weeks. The primary endpoint will focus on patient-reported outcomes in constipation. Enrollment is expected to continue through 2026, with topline data anticipated in the second half of 2027. Results from the trial have not yet been presented.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n<i>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ardelyx Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9644324-en) on January 28, 2026, and is solely responsible for the information contained therein.</span></i>\n</p>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4112","symbol_name":"金融交易所和数据","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260128:nNDL3r5P44:1","article_id":"2606781711","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2606781711","pubTimestamp":1769606954,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Ardelyx Inc. has announced the dosing of the first patient in ACCEL, a Phase 3 clinical trial evaluating IBSRELA  for the treatment of chronic idiopathic constipation  in adults. 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The multicenter, randomized, double-blind, placebo-controlled study aims to enroll approximately 700 patients, assessing the safety and efficacy of tenapanor administered twice daily over 26 weeks. The primary endpoint will focus on patient-reported outcomes in constipation. Enrollment is expected to continue through 2026, with topline data anticipated in the second half of 2027. Results from the trial have not yet been presented.\n      \n\n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ardelyx Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. 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