Alto Neuroscience Inc. announced the publication of a review article in the American Journal of Psychiatry, co-authored by members of its leadership team and board. The review consolidates clinical and translational evidence showing that disrupted neuroplasticity is a core biological driver across major psychiatric disorders such as depression, schizophrenia, PTSD, and addiction. The authors highlight the importance of developing translatable biomarkers for neuroplasticity changes in humans, a gap that Alto aims to address with its Precision Psychiatry Platform. The review supports Alto's strategy of pairing therapies with objective, circuit-level biomarkers and emphasizes the potential of targeting neuroplasticity as a measurable and druggable mechanism for improving psychiatric treatments. These results have already been published and are available online.

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