Exicure Inc. has announced the publication of results from a Phase 2 clinical study evaluating burixafor, a highly selective CXCR4 inhibitor, in the journal Annals of Hematology. The study assessed burixafor in combination with granulocyte colony-stimulating factor (G-CSF) in patients with multiple myeloma, non-Hodgkin's lymphoma, and Hodgkin disease undergoing autologous stem cell transplantation. The results showed that 92% of participants met the primary endpoint of collecting at least 5.0 × 10⁶ CD34+ cells/kg within two leukapheresis sessions, with half achieving the target in a single session. Burixafor demonstrated rapid stem cell mobilization, with peak CD34+ cell counts occurring within one hour of administration, and was generally well tolerated. Additionally, Exicure recently completed another Phase 2 study evaluating burixafor in combination with G-CSF and propranolol in multiple myeloma patients. Positive topline data from this study were presented at the American Society of Hematology $(ASH)$ Annual Meeting in December 2025 and the Tandem Meetings in February 2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Exicure Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9649073-en) on February 05, 2026, and is solely responsible for the information contained therein.