苑东生物(688513.SH)：EP-0210单抗注射液I期临床试验完成首例受试者给药

智通财经

02/09

智通财经APP讯，苑东生物(688513.SH)发布公告，公司全资子公司成都优洛生物科技有限公司自主研发的1类生物药EP-0210单抗注射液正在开展用于治疗炎症性肠病的I期临床试验，于近日完成首例受试者给药。

EP-0210单抗注射液是一款靶向人肿瘤坏死因子样配体1A(TNF-like ligand1A，TL1A)的人源化IgG1单克隆抗体药物，拟定适应症为炎症性肠病，其作用机制是通过高效结合人TL1A，阻止TL1A介导的促炎症信号通路，从而发挥治疗炎症性肠病的作用。临床前研究表明，EP-0210单抗注射液药效作用机制明确，在多种炎症性肠病体内模型中药效显著，具有良好的安全性和有效性;其在靶点活性、体内药效等方面优于国外同靶点竞品RVT-3101，有望为炎症性肠病患者带来安全有效的更多选择。

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