Abbisko Cayman (HKG:2256) subsidiary has dosed the first patient in the U.S. in the expansion phase of a global Phase 1 clinical study of its FGFR4 inhibitor irpagratinib, according to a Wednesday Hong Kong bourse filing.
The multicenter trial is evaluating irpagratinib in patients with advanced hepatocellular carcinoma with FGF19 overexpression, according to the filing.