Here are the 10 ASX-listed companies with the biggest losses on Wednesday.

Paladin Energy (ASX:PDN): -8%, AU$12.49

Westgold Resources (ASX:WGX): -6%, AU$7.46

Newmont (ASX:NEM): -5%, AU$172.86

Genesis Minerals (ASX:GMD): -5%, AU$7.67

Sims (ASX:SGM): -4%, AU$20.79

Nexgen Energy (ASX:NXG): -5%, AU$17.35

Ansell (ASX:ANN): -5%, AU$30.21

Zimplats Holdings (ASX:ZIM): -4%, AU$20.34

Capricorn Metals (ASX:CMM): -4%, AU$14.54

Yancoal Australia (ASX:YAL): -5%, AU$6.14