Wall Street's main indexes fell on Tuesday, with the S&P 500 hitting its lowest in over two months, as investors braced for the impact of a widening Middle East conflict on oil prices, inflation and global trade. .N

At 13:30 EST, the Dow Jones Industrial Average .DJI was down 0.86% at 48,485.74.The S&P 500 .SPX was down 1.00% at 6,812.52, and the Nasdaq Composite .IXIC was down 1.09% at 22,500.57.

The top three S&P 500 .PG.INX percentage gainers:

** Target Corp TGT.N, up 7.7%

** Best Buy Co Inc BBY.N, up 7.0%

** Workday Inc WDAY.OQ, up 6.0%

The top three S&P 500 .PL.INX percentage losers:

** Newmont Corporation NEM.N, down 8.4%

** Dell Technologies Inc DELL.N, down 7.0%

** Micron Technology Inc MU.OQ, down 7.0%

The top three NYSE .PG.N percentage gainers:

** BRC Inc BRCC.N, up 20.3%

** Paysafe Ltd PSFE.N, up 19.8%

** Kontoor Brands Inc KTB.N, up 18.6%

The top three NYSE .PL.N percentage losers:

** Nuvation Bio Inc NUVB.N, down 23.0%

** Sea Ltd SE.N, down 16.4%

** Alamo Group Inc ALG.N, down 14.3%

The top three Nasdaq .PG.O percentage gainers:

** MOBIX LABS, INC. MOBX.OQ, up 323.6%

** Texxon Holding Ltd NPT.OQ, up 69.6%

** Edesa Biotech Inc EDSA.OQ, up 60.1%

The top three Nasdaq .PL.O percentage losers:

** Iterum Therapeutics PLC ITRM.OQ, down 47.7%

** Scworx Corp WORX.OQ, down 35.4%

** Jiuzi Holdings Inc JZXN.OQ, down 28.1%

** Venture Global Inc VG.N:BUZZ - Surges after NY court rejects Shell bid to overturn arbitration nL6N3ZR0PZ

** Harrow Inc HROW.O:BUZZ - Slumps after forecasting annual revenue below estimates nL6N3ZR0QF

** Newmont Corp NEM.N:

** Gold Fields Ltd GFI.N:

** Sibanye Stillwater Ltd SBSW.N:

** Harmony Gold Mining Co Ltd HMY.N:

BUZZ - Gold miners drop as bullion falls on dollar strength despite safe-haven demand nL6N3ZR0R7

** MAIA Biotechnology Inc MAIA.N:BUZZ - Plunges after $30 million share sale nL4N3ZQ1F8

** On Holding Ltd ONON.N:BUZZ - Dips after muted annual sales forecast nL6N3ZR13T

** Hecla Mining Co HL.N:

** Coeur Mining Inc CDE.N:

** Endeavour Silver Corp EXK.N:

** Silvercorp Metals Inc SVM.N:

BUZZ - Silver miners fall as stronger dollar outweighs safe-haven demand nL6N3ZR0RN

** Palantir Technologies Inc PLTR.O:BUZZ - Tech billionaire Peter Thiel to dump $280 mln worth of Palantir stock; shares down nL6N3ZR0T0

** Exxon Mobil Corp XOM.N:

** Chevron Corp CVX.N:

** Occidental Petroleum Corp OXY.N:

** ConocoPhillips COP.N:

BUZZ - US energy stocks gain as expanding conflict heightens supply risks nL6N3ZR0TY

** Cheniere Energy Inc LNG.N:BUZZ - UBS raises PT on LNG exporter Cheniere Energy nL4N3ZR0VR

** Rio Tinto PLC RIO.N:

** BHP Group Ltd BHP.N:

** Southern Copper Corp SCCO.N:

** Freeport-McMoRan Inc FCX.N:

BUZZ - Copper miners fall on strong US dollar nL4N3ZR0WX

** Bimergen Energy Corp BESS.N:BUZZ - Completes acquisition of Energy Storage Project; shares up nL6N3ZR0VV

** Target Corp TGT.N:BUZZ - Rises after forecasting annual sales, profit above estimates nL6N3ZR13H

** Viper Energy Inc VNOM.O:BUZZ - Slips as Diamondback cuts stake in $798 mln secondary offering nL6N3ZR0W5

** General Electric Co GE.N:BUZZ - Bernstein hikes GE Aerospace PT on stronger engine services outlook nL4N3ZR0YQ

** Pinterest Inc PINS.N:BUZZ - Jumps after $1 billion investment from Elliott nL6N3ZR0S6

** XPO Inc XPO.N:BUZZ - BofA raises XPO's PT, expects profit growth in 2026 nL4N3ZR0ZV

** Best Buy Co Inc BBY.N:BUZZ - Jumps after quarterly profit beat estimates nL6N3ZR0XF

** NRG Energy Inc NRG.N:BUZZ - Falls after LS Power's boosted $2.3 bln share sale nL6N3ZR0XJ

** Medline Inc MDLN.O:BUZZ - Slips as sponsors look to slice stake in secondary offering nL6N3ZR0WY

** Kontoor Brands Inc KTB.N:BUZZ - Jumps after upbeat 2026 profit forecast nL6N3ZR0Y5

** Amer Sports Inc AS.N:BUZZ -Drops on $750 mln equity raise nL6N3ZR0YE

** AutoZone Inc AZO.N:BUZZ - Slips on lower quarterly profit nL4N3ZR15O

** Airbnb Inc ABNB.O:BUZZ - Gets PT hike from Mizuho on AI resilience nL4N3ZR150

** Enphase Energy Inc ENPH.O:BUZZ - Partners with Capital Good Fund for expansion; shares fall nL6N3ZR0Z2

** BrightSpring Health Services Inc BTSG.O:BUZZ - Falls as KKR chops stake in $823 mln secondary offering nL6N3ZR0ZD

** Cigna Group Inc CI.N:BUZZ - Names insider Brian Evanko as CEO, shares down nL4N3ZR16R

** Dave Inc DAVE.O:BUZZ - Rises on upbeat 2026 profit forecast nL4N3ZR18Z

** Vanda Pharmaceuticals Inc VNDA.O:BUZZ - Rises after FDA grants rare hearing on jet‑lag drug bid nL4N3ZR18Y

** Scholar Rock Holding Corp SRRK.O:BUZZ - Rises after plan to resubmit application for muscle disorder drug nL6N3ZR0ZY

** Viking Holdings Ltd VIK.N:BUZZ - Up after quarterly revenue beat estimates nL6N3ZR0ZM

** Alignment Healthcare Inc ALHC.O:BUZZ - Slips as General Atlantic cashes out nL6N3ZR10C

** Theravance Biopharma Inc TBPH.O:BUZZ - Falls as co weighs options including possible sale after drug trial failure nL4N3ZR1A7

** Blackstone Inc BX.N:

** Ares Management Corp ARES.N:

** KKR & Co Inc KKR.N:

** Blue Owl Capital Inc OWL.N:BUZZ - Alts fall as Blackstone's flagship private credit fund hit by surge in redemptions nL6N3ZR1A0

** Expedia Group Inc EXPE.O:BUZZ - Dips after Mizuho trims PT, citing weaker peer multiples nL4N3ZR1CU

** Ziff Davis Inc ZD.O:BUZZ - Eyes record daily gain after asset sale to Accenture nL6N3ZR14Q

** Surgery Partners Inc SGRY.O:BUZZ - Falls on downbeat full-year revenue outlook nL4N3ZQ1K9

**Albemarle Corp ALB.N:

** Sociedad Química y Minera de Chile SQM.N:

** Sigma Lithium Corp SGML.O:

** Lithium Americas Corp LAC.N:

BUZZ - Lithium miners dip as EV sales weaken, Middle East tensions rise nL6N3ZR15Q

** Versant Media Group Inc VSNT.O:BUZZ - Gains, posts smaller-than-expected revenue decline and share buyback nL6N3ZR17X

** United Airlines Holdings Inc UAL.O:

** Delta Air Lines Inc DAL.N:

** American Airlines Group Inc AAL.O:

** Southwest Airlines Co LUV.N:

BUZZ - US airlines dip as Middle East turmoil drives oil prices higher nL4N3ZR1QT

(Rajarshi Roy and Varun Sahay)

((Varun.sahay@thomsonreuters.com))