PepGen Shares Fall After FDA Puts Myotonic Dystrophy Trial on Hold

Dow Jones

03/05

By Nicholas G. Miller

Shares of PepGen slid after the Food and Drug Administration put a partial clinical hold on a study of its treatment for Myotonic Dystrophy, a genetic disorder that causes progressive muscle loss and weakness.

The stock fell 19% to $5.50 in Thursday's off-hours trading. It has more than doubled over the past 52 weeks.

The company said the FDA raised questions related to previously- submitted preclinical pharmacology and toxicology studies.

PepGen said it "is committed to working with the FDA to address the Agency's questions as quickly as possible."

Write to Nicholas G. Miller at nicholas.miller@wsj.com.

(END) Dow Jones Newswires

March 05, 2026 06:25 ET (11:25 GMT)

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Miller \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n  Shares of PepGen slid after the Food and Drug Administration put a partial clinical hold on a study of its treatment for Myotonic Dystrophy, a genetic disorder that causes progressive muscle loss and weakness. \n</p>\n<p>\n  The stock fell 19% to $5.50 in Thursday's off-hours trading. It has more than doubled over the past 52 weeks. \n</p>\n<p>\n  The company said the FDA raised questions related to previously- submitted preclinical pharmacology and toxicology studies. \n</p>\n<p>\n  PepGen said it \"is committed to working with the FDA to address the Agency's questions as quickly as possible.\" \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n  Write to Nicholas G. Miller at nicholas.miller@wsj.com. \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n  (END) Dow Jones Newswires\n</p>\n<p>\n  March 05, 2026 06:25 ET (11:25 GMT)\n</p>\n<p>\n  Copyright (c) 2026 Dow Jones &amp; Company, Inc.\n</p>\n</font>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"PEPG","symbol_name":"PepGen Inc.","start_time":0,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","article_id":"2617754642","we_media_id":"106","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2617754642","pubTimestamp":1772709900,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Dow Jones","introduction":"Dow Jones publishes the world’s most trusted business news and financial information in a variety of media.","home_visible":0,"id":"106","head_image":"https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99"},"summary":"Shares of PepGen slid after the Food and Drug Administration put a partial clinical hold on a study of its treatment for Myotonic Dystrophy, a genetic disorder that causes progressive muscle loss and weakness.The stock fell 19% to $5.50 in Thursday's off-hours trading. It has more than doubled over the past 52 weeks.The company said the FDA raised questions related to previously- submitted preclinical pharmacology and toxicology studies.PepGen said it \"is committed to working with the FDA to address the Agency's questions as quickly as possible.\"","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"PEPG":"PepGen Inc.","BK4139":"生物科技"},"translate_title":"FDA暂停强直性肌营养不良试验后PepGen股价下跌","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"PEPG":0.9},"content_text":"By Nicholas G. Miller \n\n\n \n\n\n  Shares of PepGen slid after the Food and Drug Administration put a partial clinical hold on a study of its treatment for Myotonic Dystrophy, a genetic disorder that causes progressive muscle loss and weakness. \n\n\n  The stock fell 19% to $5.50 in Thursday's off-hours trading. It has more than doubled over the past 52 weeks. \n\n\n  The company said the FDA raised questions related to previously- submitted preclinical pharmacology and toxicology studies. \n\n\n  PepGen said it \"is committed to working with the FDA to address the Agency's questions as quickly as possible.\" \n\n\n \n\n\n  Write to Nicholas G. Miller at nicholas.miller@wsj.com. \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  March 05, 2026 06:25 ET (11:25 GMT)\n\n\n  Copyright (c) 2026 Dow Jones & Company, Inc.","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":true,"editions":null,"column":"","sentiment":"-1","news_tag":"","news_rank":0,"isVideo":false,"video":null,"symbols":[],"gpt_button":0,"need_auth":true,"need_login_tip":false,"code":"91000000","status":"200"}}}