PegBio's GLP-1 Candidate Completes First-in-Human Dosing

MT Newswires Live

03/09

PegBio (HKG:2565) said its next-generation GLP-1 receptor agonist CR059 has completed single-dose administration in a first-in-human clinical trial and generated one-month clinical observations, according to a March 6 Hong Kong bourse filing.

Shares of the biopharmaceutical company were down nearly 2% in Monday morning trade.

The study is evaluating the safety, tolerability, and pharmacokinetic and pharmacodynamic characteristics of CR059 in patients with type 2 diabetes mellitus, the company said.

Preliminary observations four weeks after a single dose showed improvements in glycated hemoglobin, fasting blood glucose, and overall glucose control, PegBio said.

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