European equities traded in the US as American depositary receipts fell late Wednesday morning with the S&P Europe Select ADR Index dropping 0.9% to 1,734.7.

From continental Europe, the gainers were led by biopharmaceutical company Cellectis (CLLS) and petroleum refiner Equinor (EQNR), which rose 4% and 1.5%, respectively. They were followed by lenders Banco Bilbao Vizcaya Argentaria (BBVA) and ING (ING), which were up 0.3% and 0.2%, respectively.

The decliners from continental Europe were led by furniture maker Natuzzi (NTZ) and biotech firm BioNTech (BNTX), which fell 10% and 3.4%, respectively. They were followed by pharmaceutical company Novo Nordisk (NVO) and consumer goods company Unilever (UL), which were down 3.2% and 3%, respectively.

The gainers from the UK were led by biotech firm Trinity Biotech (TRIB) and oil and gas company BP (BP), which advanced 3.6% and 1.7%, respectively. They were followed by lender Barclays (BCS) and pharmaceutical company Silence Therapeutics (SLN), which increased 0.9% and 0.3%, respectively.

The decliners from the UK and Ireland were led by biopharmaceutical companies Akari Therapeutics (AKTX) and Bicycle Therapeutics (BCYC), which shed 20% and 8.7%, respectively. They were followed by biopharmaceutical company Mereo BioPharma Group (MREO) and biotech firm Autolus Therapeutics (AUTL), which dropped 3.8% and 3.2%, respectively.