MW An S&P 500 change may be imminent. These stocks are leading contenders to join the index.

By Emily Bary

With Hologic due to be acquired, Marvell, Alnylam and Veeva are among the eligible replacements, according to an analyst

Veeva Systems has the highest float-adjusted liquidity ratio among healthcare companies that are eligible for entry into the S&P 500.

It may be time for another change to the S&P 500, as Hologic will soon get acquired.

The medical-technology provider struck a go-private deal with Blackstone and TPG that's expected to close Tuesday. Since Hologic $(HOLX)$ is part of the S&P 500 SPX, Stephens analyst Melissa Roberts thinks a replacement company will be named to the index as soon as Monday evening.

She identified 14 companies that are eligible to be added to the S&P 500 outright, and another seven that are eligible for migration from the S&P MidCap 400 index MID.

The largest five eligible companies are Marvell Technology $(MRVL)$, Cheniere Energy (LNG), Ferguson Enterprises $(FERG)$, Alnylam Pharmaceuticals $(ALNY)$ and Heico $(HEI)$, Roberts noted.

See also: What's behind the new Nvidia partnership with Marvell

The committee at S&P Dow Jones Indices has latitude in determining which companies make it into the S&P 500, as long as the new entrants meet various criteria around profitability, market capitalization and more.

S&P Dow Jones Indices didn't immediately respond to a MarketWatch request for comment.

Since Hologic is a healthcare business, the committee may choose to replace it with another company in the sector. Beyond Alnylam, which makes RNA interference medicines, the life-sciences software company Veeva Systems $(VEEV)$ is the next largest eligible candidate, according to Roberts. Veeva also has the highest float-adjusted liquidity ratio among the healthcare options, she wrote.

Outside the healthcare sector, other potential contenders with strong name recognition include Reddit (RDDT), Zoom Communications (ZM) and SoFi Technologies $(SOFI)$. Reddit has the highest float-adjusted liquidity ratio among all eligible potential additions, Roberts noted, while SoFi's lower ratio on that metric and its smaller market cap reduce its chances of entry.

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-Emily Bary

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April 06, 2026 14:14 ET (18:14 GMT)

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