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International stocks trading in New York closed lower on Wednesday, as the S&P/BNY Mellon index of American depositary receipts dropped 0.4% to 259.06.

The European index fell 0.8% to 229.12. The Asian index held steady at 339.67. The Latin American index dropped 0.5% to 301.28, while the emerging-markets index dropped 0.5% to 583.36.

Adlai Nortye Ltd., based in China, posted the largest decline, plunging 16% to $13.25, followed by shares of China's Four Seasons Education (Cayman) Inc., which declined 7.7% to $10.15. Shares of Brazil-based Braskem S/A declined 7.5% to $3.70.

Australia's Immutep Ltd. was the biggest leader during the session, soaring 73% to 54 cents, and China-based XChange TEC.INC soared 70% to $1.46. VisionSys AI Inc., which is based in China, rounded out the top three leaders on Wednesday, with shares rocketing 34% to 81 cents.

Data source: Dow Jones Market Data, FactSet

(END) Dow Jones Newswires

April 15, 2026 16:30 ET (20:30 GMT)

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