Huachen AI Parking Management Technology (HCAI) shares were up 52% in Wednesday premarket activity, adding to Tuesday's gain.

Poet Technologies (POET) stock was 20% higher, extending gains from the previous session.

Kyverna Therapeutics (KYTX) shares were up 14% after the company reported overnight that a single dose of miv-cel in its KYSA-8 study "delivered rapid, statistically significant and clinically meaningful improvements" throughout all primary and secondary endpoints at 16 weeks.

Adobe (ADBE) stock was 3.1% higher, a day after the company said its board approved a new share buyback authorization, giving the company authority to buy back up to $25 billion in shares through April 30, 2030.