Regeneron Pharmaceuticals (REGN) said two dose levels of fianlimab in combination with cemiplimab, evaluated as a first-line treatment in unresectable locally advanced or metastatic melanoma, failed to meet a primary endpoint in its phase 3 trial.

The company's stock dropped 10% as intraday volume topped 2.17 million shares versus the daily average of about 685,000.

Seagate Technology's (STX) shares slumped 9.7% after CEO Dave Mosley said building new factories to meet demand would "take too long."

Intraday volume topped 3.05 million shares versus the daily average of about 3.97 million.

Air Global's (AIIR) shares fell 23% in their Nasdaq debut with volume of about 29,500.

Price: 628.30, Change: -69.95, Percent Change: -10.02