European equities traded in the US as American depositary receipts were trending lower late Tuesday morning, declining 0.3% to 1,824.16 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by software firm SAP (SAP) and internet advertising company Criteo (CRTO), which advanced 5.3% and 3.6% respectively. They were followed by biopharmaceutical company argenx (ARGX) and petroleum refiner Equinor (EQNR), which rose 2.1% and 1.3% respectively.

The decliners from continental Europe were led by semiconductor company Sequans Communications (SQNS) and telecommunications company Nokia (NOK), which dropped 3.5% and 2.7% respectively. They were followed by biopharmaceutical company Cellectis (CLLS) and medical device maker EDAP TMS (EDAP), which were off 2.6% and 1.6% respectively.

The gainers from the UK were led by biopharmaceutical companies Akari Therapeutics (AKTX) and NuCana (NCNA), which were up 4.9% and 3.5% respectively. They were followed by

biopharmaceutical company Biodexa Pharmaceuticals (BDRX) and medical device company Smith & Nephew (SNN), which were up 3.1% and 2.6% respectively.

The decliners from the UK and Ireland were led by biotech firm Autolus Therapeutics (AUTL), which fell 8%, followed by mining company BHP Group (BHP) and pharmaceutical company Silence Therapeutics (SLN), which lost 3% and 0.6% respectively.