This article was automatically generated by Dow Jones using technology from Automated Insights.

International stocks trading in New York closed lower on Wednesday, as the S&P/BNY Mellon index of American depositary receipts declined 0.5% to 269.35.

The European index dropped 0.8% to 238.14. The Asian index fell 0.2% to 358.60. The Latin American index fell 1.4% to 278.09, while the emerging-markets index rose 0.1% to 591.78.

Biodexa Pharmaceuticals PLC, based in United Kingdom, posted the largest decline, plummeting 28% to 96 cents, followed by shares of Hong Kong's Lion Group Holding Ltd., which plummeted 20% to $5.75. Shares of China-based BingEx Ltd. tumbled 17% to $1.01.

China's Jinxin Technology Holding Co. was the biggest leader during the session, soaring 37% to $3.12, and Netherlands-based LuxExperience B.V. soared 23% to $8.81. Eason Technology Ltd., which is based in China, rounded out the top three leaders on Wednesday, with shares surging 18% to 53 cents.

Data source: Dow Jones Market Data, FactSet