Perrigo Company PLC's stock plunged 5.62% in pre-market trading following the release of its fourth-quarter and full-year 2025 financial results, which revealed a significant net loss and provided guidance for the coming year that fell short of previous expectations.

The company reported a GAAP diluted earnings per share of USD -10.20 for Q4, a substantial decline from USD -0.30 in the prior year period, primarily due to a USD 1.3 billion goodwill impairment charge. While adjusted EPS was USD 0.77, it still missed the analyst consensus estimate of USD 0.79. Furthermore, the company issued its FY2026 "All In" adjusted diluted EPS guidance in a range of USD 2.00 to USD 2.30, which is below its previous FY core adjusted EPS outlook range of USD 2.25 to USD 2.55. The company also forecasted net sales growth for FY2026 to be between -5.5% and -1.5%.

Concurrently, Perrigo announced a new two-year operational enhancement program expected to deliver pre-tax annualized savings of USD 80 million to USD 100 million by the end of FY2027. The program includes a planned workforce reduction of approximately 7%. These announcements, combining a substantial quarterly loss, a guidance cut, and restructuring plans, likely contributed to negative investor sentiment and the sharp pre-market decline in the stock price.