Shares of Sage Therapeutics Inc. (SAGE) plummeted by 9.32% in premarket trading on Tuesday, October 30th, as the biopharmaceutical company reported mixed third-quarter results and faced setbacks in its pipeline.
While Sage's lead product, Zurzuvae, continued to gain traction in the postpartum depression (PPD) market, generating $22.1 million in total revenue for the quarter (up 49% from Q2), the company's overall financial performance and updates on other programs failed to impress investors.
Sage reported a net loss of $93.6 million for the third quarter, missing analyst estimates on revenue and earnings per share. The company also faced several pipeline setbacks, including the discontinuation of commercial availability for its drug Zulresso, a Phase 2 trial failure for an Alzheimer's disease candidate, and the termination of a collaboration with Biogen on the SAGE-324 program.