LEADS BIOLABS-B (09887) announced that the first patient has been successfully dosed in a Phase Ib/II clinical trial (NCT07099430) evaluating opatasumib (LBL-024), a PD-L1/4-1BB bispecific antibody, as monotherapy or combination therapy for first-line treatment of advanced melanoma.
The Phase Ib/II multicenter clinical trial is led by Professor Chen Yu from Fujian Cancer Hospital, with participation from multiple hospitals nationwide. The study aims to evaluate the efficacy and safety of opatasumib as a single agent or in combination with other agents for treating advanced melanoma.