Shares of drug developer Mira Pharma soared 46.8% in overnight trading. The company said its experimental drug, Mira-55, a non-psychoactive marijuana analog showed morphine-comparable pain relief in a preclinical animal trial.

Shares of Minim rallied 42.3% after the software provider acquired a portfolio of intellectual property and fixed assets from Suzhou Yixuntong Network Technology for $1.4 million.

Software company Datadog will be added to the S&P 500 index next week, replacing Juniper Networks after its recent acquisition by Hewlett Packard Enterprise. Shares of Datadog were up 10.6% in overnight trading. The hope of AppLovin and Robinhood being selected has once again been dashed. Their shares both dropped more than 1%.