加科思(01167)在66屆美國血液學會上展示JAB-8263治療骨髓纖維化臨床的初步數據

金吾財訊

2024/12/09

金吾財訊 | 加科思(01167)公布，公司在加利福尼亞州聖地牙哥舉行的2024年第66屆美國血液學會(「ASH」)年會上展示了BET抑制劑JAB-8263治療骨髓纖維化(MF)臨床一期的初步數據。資料顯示，JAB-8263具有良好的耐受性，二期推薦劑量為0.3毫克(每日給藥)。JAB-8263單藥治療骨髓纖維化適應症的初步療效資料是令人鼓舞的。大多數患者出現脾臟縮小(spleen volume reduction,SVR)以及總症狀評分(total symptom score，TSS)的降低。

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