** Shares of medical device maker Becton Dickinson BDX.N fall as much as 13.5% to an eight-year low of $179.09

** Stock set for its worst day since 1999, if losses hold

** BDX cuts annual profit forecast in anticipation of a potential hit from U.S. President Donald Trump's tariffs

** Co said it anticipates a $90 million impact from tariffs expense on China, majority of which will be weighted in Q4

** Co intends to invest $2.5 billion in U.S. manufacturing capacity over the next 5 years

** BDX, which has footprint in Mexico, Europe and Asia, will transfer its manufacturing facilities from China to South Carolina and Nebraska, CEO Thomas Polen said in a conference call

** Co expects its 2025 profit per share to be between $14.06 and $14.34, compared with $14.30 to $14.60 previously expected

** Co reports Q2 adj profit of $3.35 per share, beating estimates of $3.28

** As of last close, BDX had fallen 20.8% YTD

(Reporting by Siddhi Mahatole)

((siddhi.mahatole@thomsonreuters.com))