US stock indexes were mixed in late-morning trading Wednesday as investors parse new information on US trade negotiations with China and await the Federal Reserve's latest decision on interest rates to be announced later in the day.

US Treasury Secretary Scott Bessent is set to meet China's lead representative on economic matters later this week in Switzerland, the Treasury Department said Tuesday in a statement.

In company news, Advanced Micro Devices (AMD) reported Q1 non-GAAP earnings late Tuesday of $0.96 per diluted share, up from $0.62 a year earlier and above the consensus of analysts surveyed by FactSet calling for $0.94. First-quarter revenue was $7.44 billion, up from $5.47 billion a year ago and above the FactSet consensus of $7.12 billion. For Q2, the chipmaker said it expects revenue in a range of $7.1 billion to $7.7 billion. FactSet-polled analysts expect $7.22 billion. Shares of AMD were up 0.7% around midday.

Uber Technologies (UBER) reported Q1 earnings Wednesday of $0.83 per diluted share, swinging from a loss of $0.32 a year earlier and beating the FactSet consensus estimate of $0.51. First-quarter revenue was $11.53 billion, up from $10.13 billion a year ago but below the analyst consensus of $11.63 billion. For the ongoing quarter, Uber expects gross bookings to be in a range of $45.75 billion to $47.25 billion, compared to analyst estimates of $45.77 billion. Uber shares were down 1.6%.

Walt Disney (DIS) reported Q2 adjusted earnings Wednesday of $1.45 per share, up from $1.21 a year earlier and above the FactSet consensus of $1.19. Fiscal Q2 revenue was $23.62 billion, up from $22.08 billion a year earlier and above the FactSet consensus of $23.09 billion. The company said it expects full-year adjusted EPS of $5.75. Disney said Wednesday it has reached an agreement with Miral to create a theme park resort in Abu Dhabi, United Arab Emirates. Disney shares were up 10.4%.

Novo Nordisk (NVO) reported Q1 earnings Wednesday of 6.53 Danish kroner ($0.99) per diluted share, up from 5.68 kroner a year earlier and above the FactSet consensus of 6.11 kroner. First-quarter sales were 78.09 billion kroner, up from 65.35 billion kroner a year ago and above the FactSet consensus of 77.94 billion kroner. For full-year 2025, the company lowered its sales growth guidance to a range of 13% to 21% from 16% to 24%. It also lowered its operating profit growth guidance to 16% to 24% from 19% to 27%. Novo Nordisk shares were up 1.9%.

Ford Motor (F) is raising prices on three models produced in Mexico due to President Donald Trump's tariffs, Reuters reported Wednesday, citing a notice sent to dealers it reviewed. The new prices on the Mustang Mach-E electric SUV, Maverick pickup truck and Bronco Sport went into effect on May 2 and will result in price increases of as much as $2,000 on some models, Reuters reported. Ford shares were down 1.3%.

CrowdStrike Holdings (CRWD) plans to reduce its global workforce by 500 positions, or 5%, the company said Wednesday in a regulatory filing. CrowdStrike shares were down 4.1%.

Alphabet's (GOOG) Google said Wednesday it will provide early-stage capital to help Elementl Power prepare three potential US sites for advanced nuclear projects. Each site will aim for at 600 megawatts of capacity, Google said. Shares of Google were down 4.6%.

Price: 98.88, Change: +0.26, Percent Change: +0.26