When it comes to long-term investing, you can't just buy any old ASX 200 share.

You need to focus on companies that stand out for their resilience, innovation, and ability to grow through the cycles. These are the businesses that don't just survive changing market conditions — they thrive, compound, and reward patient shareholders along the way.

With that in mind, let's take a look at three amazing ASX 200 shares that analysts rate as buys and could be great buy and hold options.

CSL Ltd (ASX: CSL)

The first ASX 200 share that could be a great buy and hold option is CSL. It is a global leader in biotechnology, specialising in plasma-derived therapies, vaccines, and cutting-edge medical treatments.

With a global presence, CSL operates three powerhouse businesses — CSL Behring, CSL Vifor, and CSL Seqirus. The company also continues to invest heavily in R&D, ensuring it stays at the forefront of medical innovation.

Despite its size, CSL still has plenty of room to grow to grow in the future. Particularly with rising demand for immunoglobulin therapies and new (and potentially lucrative) products in its pipeline.

Bell Potter has a buy rating and $335.00 price target on its shares.

REA Group Ltd (ASX: REA)

Another ASX 200 share that could be a top buy and hold pick is REA Group. It is the company behind realestate.com.au, which is a digital real estate advertising powerhouse and one of the most profitable online businesses in the country. It dominates the Australian property portal space and has successfully expanded into international markets, including India.

What makes REA Group special is its network effect and pricing power. It consistently delivers strong returns through digital advertising, premium listings, and data-driven products for agents, buyers, and sellers.

Even during softer periods for property listings, REA manages to grow through higher yields and innovation. And with a robust balance sheet, strong margins, and expanding ecosystem, it is arguably one of the most compelling long-term plays on the Australian share market.

UBS has a buy rating and $290.00 price target on its shares.

Temple & Webster Group Ltd (ASX: TPW)

Finally, for investors seeking exposure to ecommerce, Temple & Webster could be one to buy and hold.

Specialising in online furniture and homewares, the company has become a clear category leader in a space that's historically lagged digital transformation. Its capital-light model, agile marketing strategy, and focus on artificial intelligence give it a structural edge.

And as consumer behaviour continues shifting online, Temple & Webster is positioned to capture a growing share of the $16 billion+ furniture and homewares market in Australia. In addition, with strong gross margins and a clear path to higher operating leverage, this ASX 200 share is a digital growth story that's only really getting started.

Citi currently has a buy rating and $21.10 price target on the company's shares.