Bruker Corporation has unveiled the timsMetabo mass spectrometer, designed to significantly enhance sensitivity and specificity in 4D-Metabolomics and 4D-Lipidomics. This breakthrough technology leverages 4D LC-TIMS-MS/MS separations and CCS measurements, offering unparalleled specificity and annotation confidence. A notable feature is the introduction of the 'digital metabolome archive' for AI/ML scaling, supported by the new TIMS Mobility Range Enhancement (MoRE) technology. The QSee™ QC suite, alongside the cloud-based TwinScape™, ensures performance monitoring for reliable metabolomics research. Enhanced TASQ® RealTimeQC capabilities now offer improved data visualization, crucial for intra-batch data quality monitoring. According to Professor Thomas Moritz from the University of Copenhagen, these advancements provide essential quality monitoring, supporting informed decision-making during analysis. Dr. Matthew Lewis of Bruker highlighted the timsMetabo as a transformative innovation in the field, focusing on customer needs and delivering advanced features for data analysis and quality assurance.