TNF Pharmaceuticals Partners with DADA2 Foundation for Compassionate Use Study of Isomyosamine in Rare Pediatric Disease

Reuters
2025/06/24
TNF Pharmaceuticals Partners with DADA2 Foundation for Compassionate Use Study of Isomyosamine in Rare Pediatric Disease

TNF Pharmaceuticals Inc. (Nasdaq: TNFA) has announced a new philanthropic collaboration with the DADA2 Foundation to initiate a Compassionate Use (Expanded Access) study of their lead candidate, isomyosamine. This study will evaluate isomyosamine as a potential treatment for the rare pediatric autoinflammatory disease, DADA2 (Deficiency of Adenosine Deaminase 2). Isomyosamine is a novel small molecule TNF-alpha inhibitor that offers an orally administered alternative to standard-of-care biological treatments for DADA2, with the advantage of minimal or no immunosuppression. The study aims to assess its effectiveness in addressing the hyperinflammatory and vasculitic aspects of DADA2, a condition primarily affecting children. The results of this study have not yet been presented.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. TNF Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20250624517572) on June 24, 2025, and is solely responsible for the information contained therein.

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