Genor Biopharma Announces Progress in Clinical Evaluation of Novel T-Cell Engager GB261 for Autoimmune Diseases

Reuters

2025/06/30

Genor Biopharma Announces Progress in Clinical Evaluation of Novel T-Cell Engager GB261 for Autoimmune Diseases

Genor Biopharma Holdings Ltd. has announced advancements in the clinical evaluation of GB261, a novel T-cell engager. Candid Therapeutics, Inc., the licensee of GB261, has initiated clinical trials targeting autoimmune diseases, with the first patients having been dosed and reportedly tolerating the treatment well. The company has also established a subcutaneous dosing formulation for GB261. This bispecific antibody is designed to target CD20 on B-cells and CD3 on T-cells, aiming to mediate cytotoxicity against CD20-expressing B-cells while minimizing excessive T-cell activation. A phase I/II open-label multi-center study for relapsed/refractory B-cell non-Hodgkin's lymphoma has been completed in China and Australia. There is no assurance provided regarding the successful development and marketing of GB261.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Genor Biopharma Holdings Ltd. published the original content used to generate this news brief on June 30, 2025, and is solely responsible for the information contained therein.

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Candid <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a>, Inc., the licensee of GB261, has initiated clinical trials targeting autoimmune diseases, with the first patients having been dosed and reportedly tolerating the treatment well. The company has also established a subcutaneous dosing formulation for GB261. This bispecific antibody is designed to target CD20 on B-cells and CD3 on T-cells, aiming to mediate cytotoxicity against CD20-expressing B-cells while minimizing excessive T-cell activation. A phase I/II open-label multi-center study for relapsed/refractory B-cell non-Hodgkin's lymphoma has been completed in China and Australia. There is no assurance provided regarding the successful development and marketing of GB261.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Genor Biopharma Holdings Ltd. published the original content used to generate this news brief on June 30, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK1161","symbol_name":"生物科技","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250630:nNDL8YwvMm:1","article_id":"2548301610","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2548301610","pubTimestamp":1751298918,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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Candid Therapeutics, Inc., the licensee of GB261, has initiated clinical trials targeting autoimmune diseases, with the first patients having been dosed and reportedly tolerating the treatment well. The company has also established a subcutaneous dosing formulation for GB261. This bispecific antibody is designed to target CD20 on B-cells and CD3 on T-cells, aiming to mediate cytotoxicity against CD20-expressing B-cells while minimizing excessive T-cell activation. A phase I/II open-label multi-center study for relapsed/refractory B-cell non-Hodgkin's lymphoma has been completed in China and Australia. There is no assurance provided regarding the successful development and marketing of GB261.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. 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