Xenetic Biosciences Announces Initiation of Exploratory Clinical Study on DNase I for Pancreatic Cancer Treatment in Israel
Xenetic Biosciences, Inc. has announced that its collaboration partner, PeriNess Ltd., has initiated patient dosing in an exploratory clinical study at Bnei Zion Medical Center in Israel. The study is investigating the use of systemic recombinant human DNase I in combination with FOLFIRINOX for the first-line treatment of unresectable, locally advanced, or metastatic pancreatic cancer. Dr. Abed Agbabrya, head of Oncology at Bnei Zion Hospital, is the principal investigator. The study aims to explore the potential of DNase I to improve treatment outcomes by degrading neutrophil extracellular traps (NETs) in the pancreatic cancer tumor microenvironment. Results from this study have not yet been presented.
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