Verastem股價在LGSOC治療數據發表於醫學期刊後上漲

英為財情

2025/07/12

Investing.com -- 在公司宣佈其RAMP 201二期臨床試驗的主要分析數據發表在《臨床腫瘤學雜誌》(Journal of Clinical Oncology)後，Verastem Inc (NASDAQ:VSTM)股價上漲3.5%。已發表的數據顯示，avutometinib聯合defactinib治療複發性低級別漿液性卵巢癌(LGSOC)的所有患者中，確認的總體響應率為31%。在...

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height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nVerastem股價在LGSOC治療數據發表於醫學期刊後上漲\n</h2>\n<h4 class=\"meta\">\n<p class=\"head\">\n<strong class=\"h-name small\">英為財情</strong><span class=\"h-time small\">2025-07-12 04:19</span>\n</p>\n</h4>\n</header>\n<article>\n<div>\n<p>Investing.com -- 在公司宣佈其RAMP 201二期臨床試驗的主要分析數據發表在《臨床腫瘤學雜誌》(Journal of Clinical Oncology)後，Verastem Inc (NASDAQ:VSTM)股價上漲3.5%。\n已發表的數據顯示，avutometinib聯合defactinib治療複發性低級別漿液性卵巢癌(LGSOC)的所有患者中，確認的總體響應率為31%。在...</p>\n\n<a href=\"https://cn.investing.com/news/stock-market-news/article-93CH-2882686\">網頁鏈接</a>\n\n</div>\n\n<div class=\"bt-text\">\n\n\n<p> 來源：<a href=\"https://cn.investing.com/news/stock-market-news/article-93CH-2882686\">英為財情</a></p>\n<p>為提升您的閱讀體驗，我們對本頁面進行了排版優化</p>\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4139","symbol_name":"生物科技","start_time":0,"source_url":"https://cn.investing.com/news/stock-market-news/article-93CH-2882686","article_id":"2550964210","we_media_id":null,"thumbnails":[],"rights":{"source":"investing_news","url":"https://cn.investing.com/news/stock-market-news/article-93CH-2882686","rn_cache_url":null,"directOrigin":true},"url":"https://stock-news.laohu8.com/highlight/detail?id=2550964210","pubTimestamp":1752265140,"columns":[],"sourceInfo":{"source_id":"investing_news","name":"英为财情新闻"},"weMediaInfo":null,"summary":"Investing.com -- 在公司宣佈其RAMP 201二期臨床試驗的主要分析數據發表在《臨床腫瘤學雜誌》後，Verastem Inc 股價上漲3.5%。已發表的數據顯示，avutometinib聯合defactinib治療複發性低級別漿液性卵巢癌的所有患者中，確認的總體響應率為31%。在KRAS突變患者中，響應率明顯更高，達到44%，而KRAS野生型患者的響應率為17%。Verastem目前正在進行一項全球性的RAMP 301三期試驗，評估這種聯合療法在有和沒有KRAS突變的複發性LGSOC患者中的效果。","collect":0,"end_time":0,"defaultTopTitle":"investing.com","property":[],"viewcount":null,"language":"zh","relate_stocks":{"BK4139":"生物科技","VSTM":"Verastem"},"translate_title":"Verastem Stock Rises After LGSOC Treatment Data Published in Medical Journal","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"VSTM":1},"content_text":"Investing.com -- 在公司宣佈其RAMP 201二期臨床試驗的主要分析數據發表在《臨床腫瘤學雜誌》(Journal of Clinical Oncology)後，Verastem Inc (NASDAQ:VSTM)股價上漲3.5%。\n已發表的數據顯示，avutometinib聯合defactinib治療複發性低級別漿液性卵巢癌(LGSOC)的所有患者中，確認的總體響應率為31%。在KRAS突變患者中，響應率明顯更高，達到44%，而KRAS野生型患者的響應率為17%。\n這些發現支持了美國食品藥品監督管理局(FDA)最近批准的這一聯合療法用於治療KRAS突變的複發性LGSOC。Verastem計劃向美國國家綜合癌症網絡(National Comprehensive Cancer Network)提交該出版物，以支持將KRAS野生型人羣納入臨床實踐指南。\n根據已發表的結果，\"無論KRAS突變狀態如何，大多數患者(82%)的靶病灶都有所減少。\"所有患者的中位響應持續時間為31.1個月，KRAS突變人羣的中位響應持續時間也相同，而所有患者的中位無進展生存期為12.9個月，KRAS突變人羣為22.0個月。\n該試驗的全球首席研究員Susana Banerjee教授指出，這種聯合治療展示了\"具有臨床意義且持久的響應\"，並強調其\"有潛力成為複發性低級別漿液性卵巢癌的新標準治療方案\"。\n據報道，該治療耐受性良好，僅10%的患者因不良事件而停止治療。常見的副作用包括噁心、腹瀉和肌酸磷酸激酶水平升高。\nVerastem目前正在進行一項全球性的RAMP 301三期試驗，評估這種聯合療法在有和沒有KRAS突變的複發性LGSOC患者中的效果。\n\n本文由人工智能協助翻譯。更多信息，請參見我們的使用條款。","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"dataReport","news_rank":0,"symbols":[],"gpt_button":1,"need_auth":false,"code":"91000000","status":"200"}}}