Asian equities traded in the US as American depositary receipts were lower Wednesday morning, declining 1.0% to 2,329.40 on the S&P Asia 50 ADR Index.

From North Asia, the gainers were led by diagnostic imaging centers company Concord Medical Services (CCM) and computer hardware maker Canaan (CAN), which climbed 16% and 7.6%, respectively. They were followed by brand platform Baozun (BZUN) and online game developer The9 (NCTY), which advanced 7.4% and 3.9%, respectively.

The decliners from North Asia were led by pet-focused platform Boqii (BQ) and ecommerce company Baidu (BIDU), which fell 9% and 7.1%, respectively. They were followed by electric vehicle maker NIO (NIO) and online brokerage UP Fintech (TIGR), which dropped 5.1% and 4%, respectively.

From South Asia, the gainers were led by IT firms Sify Technologies (SIFY) and Wipro (WIT), which rose 7.1% and 1.9%, respectively. They were followed by IT company Infosys (INFY) and tech conglomerate Sea (SE), which were up 0.9% and 0.4%, respectively.

The decliners from South Asia were led by financial services company ICICI Bank (IBN), which lost 0.3%. It was followed by financial services company HDFC Bank (HDB) and pharmaceutical company Dr. Reddy's Laboratories (RDY), which were off 0.1% each.