CytoMed Therapeutics Ltd. Advances ANGELICA Trial to Dose Level 2 for Treatment of Advanced Solid Tumors and Haematological Malignancies

Reuters

07/21

CytoMed <a href="https://laohu8.com/S/LENZ">Therapeutics</a> Ltd. Advances ANGELICA Trial to Dose Level 2 for Treatment of Advanced Solid Tumors and Haematological Malignancies

CytoMed Therapeutics Ltd., a clinical stage biopharmaceutical company based in Singapore, has announced the completion of dose level 1 in its ANGELICA Trial, a Phase I dose-escalation clinical trial. The trial evaluates the safety and tolerability of CTM-N2D, an allogeneic NKG2DL-targeting chimeric antigen receptor-grafted $(CAR)$ gamma delta T cell therapy, in patients with advanced solid tumors or haematological malignancies. The trial will now proceed to dose level 2, scheduled to begin in the third quarter of 2025. CTM-N2D utilizes gamma delta T cells from healthy donors, modified to target cancer cells, and can be administered without donor-patient compatibility matching. Further results from the trial have not yet been presented.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Cytomed Therapeutics Ltd. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission (Ref. ID: 0001641172-25-020369), on July 21, 2025, and is solely responsible for the information contained therein.

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Advances ANGELICA Trial to Dose Level 2 for Treatment of Advanced Solid Tumors and Haematological Malignancies","media":"Reuters","content":"<html xmlns=\"http://www.w3.org/1999/xhtml\" xmlns:newsg2=\"http://iptc.org/std/nar/2006-10-01/\" xmlns:xhtml=\"http://www.w3.org/1999/xhtml\"><head><title>\n      CytoMed <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> Ltd. Advances ANGELICA Trial to Dose Level 2 for Treatment of Advanced Solid Tumors and Haematological Malignancies\n    </title></head><body><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n        CytoMed Therapeutics Ltd., a clinical stage biopharmaceutical company based in Singapore, has announced the completion of dose level 1 in its ANGELICA Trial, a Phase I dose-escalation clinical trial. 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Advances ANGELICA Trial to Dose Level 2 for Treatment of Advanced Solid Tumors and Haematological Malignancies\n</h2>\n<h4 class=\"meta\">\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1032215980\">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Reuters </p>\n<p class=\"h-time smaller\">2025-07-21 22:00</p>\n</div>\n</a>\n</h4>\n</header>\n<article>\n<html xmlns=\"http://www.w3.org/1999/xhtml\" xmlns:newsg2=\"http://iptc.org/std/nar/2006-10-01/\" xmlns:xhtml=\"http://www.w3.org/1999/xhtml\"><head><title>\n      CytoMed <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> Ltd. Advances ANGELICA Trial to Dose Level 2 for Treatment of Advanced Solid Tumors and Haematological Malignancies\n    </title></head><body><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n        CytoMed Therapeutics Ltd., a clinical stage biopharmaceutical company based in Singapore, has announced the completion of dose level 1 in its ANGELICA Trial, a Phase I dose-escalation clinical trial. The trial evaluates the safety and tolerability of CTM-N2D, an allogeneic NKG2DL-targeting chimeric antigen receptor-grafted <a href=\"https://laohu8.com/S/CAR\">$(CAR)$</a> gamma delta T cell therapy, in patients with advanced solid tumors or haematological malignancies. The trial will now proceed to dose level 2, scheduled to begin in the third quarter of 2025. CTM-N2D utilizes gamma delta T cells from healthy donors, modified to target cancer cells, and can be administered without donor-patient compatibility matching. Further results from the trial have not yet been presented.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Cytomed Therapeutics Ltd. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission (Ref. ID: 0001641172-25-020369), on July 21, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4139","symbol_name":"生物科技","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250721:nNDL2nxGKd:1","article_id":"2553777074","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2553777074","pubTimestamp":1753106450,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"CytoMed Therapeutics Ltd. Advances ANGELICA Trial to Dose Level 2 for Treatment of Advanced Solid Tumors and Haematological Malignancies. Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 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Advances ANGELICA Trial to Dose Level 2 for Treatment of Advanced Solid Tumors and Haematological Malignancies\n    \n\n        CytoMed Therapeutics Ltd., a clinical stage biopharmaceutical company based in Singapore, has announced the completion of dose level 1 in its ANGELICA Trial, a Phase I dose-escalation clinical trial. The trial evaluates the safety and tolerability of CTM-N2D, an allogeneic NKG2DL-targeting chimeric antigen receptor-grafted $(CAR)$ gamma delta T cell therapy, in patients with advanced solid tumors or haematological malignancies. The trial will now proceed to dose level 2, scheduled to begin in the third quarter of 2025. CTM-N2D utilizes gamma delta T cells from healthy donors, modified to target cancer cells, and can be administered without donor-patient compatibility matching. Further results from the trial have not yet been presented.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. 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