Adagene Inc. has reported a net loss attributable to its shareholders of $13.5 million for the six months ended June 30, 2025, compared to a net loss of $17.0 million in the same period of 2024. The company noted a decrease in research and development expenses, which fell to $12.0 million from $14.7 million in the previous year, reflecting a strategic focus on their anti-CTLA-4 SAFEbody ADG126. Administrative expenses showed a slight increase, reaching $3.7 million from $3.6 million in the prior year. As of June 30, 2025, Adagene reported cash and cash equivalents of $62.8 million, a decrease from $85.2 million as of December 31, 2024. Additionally, total borrowings from commercial banks in China decreased significantly to $6.6 million from $18.2 million. In corporate updates, Adagene appointed John Maraganore, Ph.D. as Executive Advisor in April to aid in strategic guidance and growth. In May, Mickael Chane-Du joined as Chief Strategy Officer to enhance financing, strategic planning, and business development efforts.