Amarin Corporation Unveils New Study on Eicosapentaenoic Acid's Potential Anti-Inflammatory Mechanisms at ESC 2025

Reuters
08/31
Amarin Corporation Unveils New Study on Eicosapentaenoic Acid's Potential Anti-Inflammatory Mechanisms at ESC 2025

Amarin Corporation plc $(AMRN)$ has announced new findings from in vitro studies presented at the European Society of Cardiology (ESC) Congress 2025 in Madrid, Spain. The data provides insights into the potential mechanisms of action for the company's drug, VASCEPA®/VAZKEPA®, specifically involving eicosapentaenoic acid (EPA). The studies focused on the effects of EPA on lipoprotein(a) [Lp(a)] oxidation and its role in reducing cellular stress and inflammatory protein expression in endothelial cells. Preliminary results suggest that EPA may exert anti-inflammatory effects by modulating the nod-like receptor protein-3 (NLRP3) inflammasome in monocyte-derived macrophages. These findings indicate that EPA's benefits may extend beyond triglyceride lowering, potentially influencing cardiovascular risk factors through mechanisms such as autophagy and inflammasome activity.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Amarin Corporation plc published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9520081-en) on August 31, 2025, and is solely responsible for the information contained therein.

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