Moderna Says New Covid-19 Vaccine Generates Strong Response Against Variant

Dow Jones
09/16
 

By Nicholas G. Miller

 

Moderna said the 2025-2026 formula of its Covid-19 vaccine produced a strong immune response against the dominant LP.8.1 variant.

The company said a preliminary analysis from a phase four clinical trial showed the new formula of its Spikevax vaccine generated an eight-fold increase in LP.8.1-neutralizing antibodies.

No new safety concerns of the vaccine were identified.

Spikevax is approved for individuals six months through 64 years of age with at least one underlying condition that puts them at higher risk for Covid-19, and all adults 65 years and older.

The company said CDC data from U.S. wastewater shows Covid-19 activity is high, with LP.8.1 and its familial strains continuing to dominate.

Earlier this month, Pfizer and BioNTech said the updated formula of their Covid-19 vaccine generated a strong response against the variant.

A phase three trial showed a four-fold increase in LP.8.1-neutralizing antibodies.

 

Write to Nicholas G. Miller at nicholas.miller@wsj.com.

 

(END) Dow Jones Newswires

September 16, 2025 06:30 ET (10:30 GMT)

Copyright (c) 2025 Dow Jones & Company, Inc.

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