Applied Therapeutics Says Path Forward Not Determined for Govorestat; Shares Fall Pre-Bell

MT Newswires Live

2025/09/29

Applied Therapeutics (APLT) said Monday that a path forward for its new drug application for govorestat to treat Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency has not been determined.

The company said it completed a meeting with the US Food and Drug Administration to discuss the potential submission in Q3.

Applied Therapeutics said it is waiting for the official meeting minutes from the FDA to decide on the next steps.

Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency is a genetic metabolic disease.

Shares of Applied Therapeutics were down more than 60% in recent Monday premarket activity.

Price: 0.49, Change: -0.75, Percent Change: -60.51

免責聲明：投資有風險，本文並非投資建議，以上內容不應被視為任何金融產品的購買或出售要約、建議或邀請，作者或其他用戶的任何相關討論、評論或帖子也不應被視為此類內容。本文僅供一般參考，不考慮您的個人投資目標、財務狀況或需求。TTM對信息的準確性和完整性不承擔任何責任或保證，投資者應自行研究並在投資前尋求專業建議。

熱議股票

{"basename":"/hant","ssrTDKData":{"titleTemplate":"%s - 老虎證券","title":"老虎证券全球投资理财平台| 一站式投资美股新股港股A股","description":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","keywords":"老虎證券,老虎證券開戶,老虎券商,老虎證券官網,老虎證券app,tigertrade老虎證券,股票,炒股,新加坡股票交易平臺,投資,投資理財","social":{"ogDescription":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.be62fbe1.png","ogUrl":"https://www.itiger.com/hant/news/2571216380"},"companyName":"老虎證券"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental"},"isCrawlerRequest":true,"__swrFallback__":{"@#url:\"https://stock-news.skytigris.cn/v3/news\",params:#id:\"2571216380\",edition:\"fundamental\",auth_exemption:1,,,undefined,":{"share":"https://ttm.financial/m/news/2571216380?lang=zh_TW&edition=fundamental","thumbnail":"","is_english":true,"pubTime":"2025-09-29 19:43","share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","id":"2571216380","market":"nz","top_or_hot":-1,"title":"Applied Therapeutics Says Path Forward Not Determined for Govorestat; Shares Fall Pre-Bell","media":"MT Newswires Live","content":"<html><body><p> <a href=\"https://laohu8.com/S/AMAT\">Applied</a> <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> (APLT) said Monday that a path forward for its new drug application for govorestat to treat Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency has not been determined.</p><p>The company said it completed a meeting with the US Food and Drug Administration to discuss the potential submission in Q3.</p><p>Applied Therapeutics said it is waiting for the official meeting minutes from the FDA to decide on the next steps.</p><p>Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency is a genetic metabolic disease.</p><p>Shares of Applied Therapeutics were down more than 60% in recent Monday premarket activity.</p><p>Price: 0.49, Change: -0.75, Percent Change: -60.51</p></body></html>","source":"mtnewswires_news","html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Applied Therapeutics Says Path Forward Not Determined for Govorestat; Shares Fall Pre-Bell</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nApplied Therapeutics Says Path Forward Not Determined for Govorestat; Shares Fall Pre-Bell\n</h2>\n<h4 class=\"meta\">\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1092851196\">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://community-static.tradeup.com/news/3002d84abbd5ace3c99397c7f95b8d4e);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">MT Newswires Live </p>\n<p class=\"h-time smaller\">2025-09-29 19:43</p>\n</div>\n</a>\n</h4>\n</header>\n<article>\n<html><body><p> <a href=\"https://laohu8.com/S/AMAT\">Applied</a> <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> (APLT) said Monday that a path forward for its new drug application for govorestat to treat Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency has not been determined.</p><p>The company said it completed a meeting with the US Food and Drug Administration to discuss the potential submission in Q3.</p><p>Applied Therapeutics said it is waiting for the official meeting minutes from the FDA to decide on the next steps.</p><p>Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency is a genetic metabolic disease.</p><p>Shares of Applied Therapeutics were down more than 60% in recent Monday premarket activity.</p><p>Price: 0.49, Change: -0.75, Percent Change: -60.51</p></body></html>\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4007","symbol_name":"製藥","start_time":0,"source_url":"https://www.mtnewswires.com/","article_id":"2571216380","we_media_id":"1092851196","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2571216380","pubTimestamp":1759146236,"columns":[],"sourceInfo":{"source_id":"mtnewswires_news","name":"MT Newswires"},"weMediaInfo":{"media_name":"MT Newswires Live","introduction":"The most recognized names in North America, Europe and Asia rely on MT Newswires to power their applications. Better news, better service, better price.","home_visible":1,"id":"1092851196","head_image":"https://community-static.tradeup.com/news/3002d84abbd5ace3c99397c7f95b8d4e"},"summary":"Applied Therapeutics  said Monday that a path forward for its new drug application for govorestat to treat Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency has not been determined.The company said it completed a meeting with the US Food and Drug Administration to discuss the potential submission in Q3.Applied Therapeutics said it is waiting for the official meeting minutes from the FDA to decide on the next steps.Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency is a genetic metabolic disease.Shares of Applied Therapeutics were down more than 60% in recent Monday premarket activity.Price: 0.49, Change: -0.75, Percent Change: -60.51","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"BK4007":"制药","BK4145":"电子制造服务","LU0109394709.USD":"富兰克林生物科技新领域基金A (acc)","APLT":"Applied Therapeutics Inc.","BK4539":"次新股","BK4202":"服装、服饰与奢侈品","LU0889565916.HKD":"FRANKLIN BIOTECHNOLOGY DISCOVERY \"A\" (HKD) ACC","LU0320765992.SGD":"FTIF - Franklin Biotechnology Discovery A Acc SGD","BK4139":"生物科技","LENZ":"Therapeutics"},"translate_title":"Applied Therapeutics表示Govorestat的前进道路尚未确定；盘前股价下跌","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"APLT":1,"FORD":1.5,"LENZ":1.5},"content_text":"Applied Therapeutics (APLT) said Monday that a path forward for its new drug application for govorestat to treat Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency has not been determined.The company said it completed a meeting with the US Food and Drug Administration to discuss the potential submission in Q3.Applied Therapeutics said it is waiting for the official meeting minutes from the FDA to decide on the next steps.Charcot-Marie-Tooth Sorbitol Dehydrogenase deficiency is a genetic metabolic disease.Shares of Applied Therapeutics were down more than 60% in recent Monday premarket activity.Price: 0.49, Change: -0.75, Percent Change: -60.51","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"-1","news_tag":"","news_rank":0,"symbols":[],"gpt_button":1,"need_auth":false,"code":"91000000","status":"200"}}}