** Shares of drug developer Bolt Biotherapeutics BOLT.O fall 13.6% to $4.89 premarket
** Co said on Wednesday it is modifying the design of its early-stage trial for cancer drug BDC-4182, and now expects to release initial data in the third quarter of 2026
** The updated protocol will include step-up dosing, a method used in similar therapies to help reduce side effects, co said
** Co is also cutting about 50% of its workforce to extend its cash runway into 2027
** As of last close, stock down 47% YTD
(Reporting by Kamal Choudhury in Bengaluru)
((Kamal.Choudhury@thomsonreuters.com;))