Spyre Therapeutics Up Over 19%, on Pace for Largest Percent Increase Since November 2023 -- Data Talk

Dow Jones

2025/10/10

Spyre Therapeutics, Inc (SYRE) is currently at $21.14, up $3.46 or 19.54%

--Would be highest close since Feb. 24, 2025, when it closed at $21.26

--On pace for largest percent increase since Nov. 28, 2023, when it rose 20.73%

--Currently up three of the past four days

--Currently up two consecutive days; up 31.93% over this period

--Best two-day stretch since the two days ending June 23, 2023, when it rose 275.94%

--Up 26.1% month-to-date

--Down 9.21% year-to-date; on pace for worst year since 2022, when it fell 90.53%

--Down 92.95% from its all-time closing high of $299.75 on April 8, 2016

--Down 22.35% from 52 weeks ago (Oct. 10, 2024), when it closed at $27.22

--Down 46.6% from its 52-week closing high of $39.58 on Nov. 8, 2024

--Up 79.11% from its 52-week closing low of $11.80 on April 8, 2025

--Traded as high as $21.25; highest intraday level since Feb. 26, 2025, when it hit $21.50

--Up 20.19% at today's intraday high; largest intraday percent increase since March 1, 2024, when it rose as much as 20.23%

All data as of 1:33:51 PM ET

Source: Dow Jones Market Data, FactSet

(END) Dow Jones Newswires

October 09, 2025 13:37 ET (17:37 GMT)

Copyright (c) 2025 Dow Jones & Company, Inc.

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up 31.93% over this period \n</p>\n<p>\n     --Best two-day stretch since the two days ending June 23, 2023, when it rose 275.94% \n</p>\n<p>\n     --Up 26.1% month-to-date \n</p>\n<p>\n     --Down 9.21% year-to-date; on pace for worst year since 2022, when it fell 90.53% \n</p>\n<p>\n     --Down 92.95% from its all-time closing high of $299.75 on April 8, 2016 \n</p>\n<p>\n     --Down 22.35% from 52 weeks ago (Oct. 10, 2024), when it closed at $27.22 \n</p>\n<p>\n     --Down 46.6% from its 52-week closing high of $39.58 on Nov. 8, 2024 \n</p>\n<p>\n     --Up 79.11% from its 52-week closing low of $11.80 on April 8, 2025 \n</p>\n<p>\n     --Traded as high as $21.25; highest intraday level since Feb. 26, 2025, when it hit $21.50 \n</p>\n<p>\n     --Up 20.19% at today's intraday high; largest intraday percent increase since March 1, 2024, when it rose as much as 20.23% \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     All data as of 1:33:51 PM ET \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     Source: Dow Jones Market Data, FactSet \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n  (END) Dow Jones Newswires\n</p>\n<p>\n  October 09, 2025 13:37 ET (17:37 GMT)\n</p>\n<p>\n  Copyright (c) 2025 Dow Jones &amp; Company, Inc.\n</p>\n</font>","source":null,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Spyre Therapeutics Up Over 19%, on Pace for Largest Percent Increase Since November 2023 -- Data Talk</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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up 31.93% over this period \n</p>\n<p>\n     --Best two-day stretch since the two days ending June 23, 2023, when it rose 275.94% \n</p>\n<p>\n     --Up 26.1% month-to-date \n</p>\n<p>\n     --Down 9.21% year-to-date; on pace for worst year since 2022, when it fell 90.53% \n</p>\n<p>\n     --Down 92.95% from its all-time closing high of $299.75 on April 8, 2016 \n</p>\n<p>\n     --Down 22.35% from 52 weeks ago (Oct. 10, 2024), when it closed at $27.22 \n</p>\n<p>\n     --Down 46.6% from its 52-week closing high of $39.58 on Nov. 8, 2024 \n</p>\n<p>\n     --Up 79.11% from its 52-week closing low of $11.80 on April 8, 2025 \n</p>\n<p>\n     --Traded as high as $21.25; highest intraday level since Feb. 26, 2025, when it hit $21.50 \n</p>\n<p>\n     --Up 20.19% at today's intraday high; largest intraday percent increase since March 1, 2024, when it rose as much as 20.23% \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     All data as of 1:33:51 PM ET \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n     Source: Dow Jones Market Data, FactSet \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n  (END) Dow Jones Newswires\n</p>\n<p>\n  October 09, 2025 13:37 ET (17:37 GMT)\n</p>\n<p>\n  Copyright (c) 2025 Dow Jones &amp; Company, Inc.\n</p>\n</font>\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4139","symbol_name":"生物科技","start_time":0,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","article_id":"2574607621","we_media_id":"106","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2574607621","pubTimestamp":1760031420,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Dow Jones","introduction":"Dow Jones publishes the world’s most trusted business news and financial information in a variety of media.","home_visible":0,"id":"106","head_image":"https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99"},"summary":"Spyre Therapeutics, Inc  is currently at $21.14, up $3.46 or 19.54%. --Would be highest close since Feb. 24, 2025, when it closed at $21.26. --On pace for largest percent increase since Nov. 28, 2023, when it rose 20.73%. --Currently up two consecutive days; up 31.93% over this period. --Down 9.21% year-to-date; on pace for worst year since 2022, when it fell 90.53%. --Down 92.95% from its all-time closing high of $299.75 on April 8, 2016. --Down 22.35% from 52 weeks ago , when it closed at $27.22. --Traded as high as $21.25; highest intraday level since Feb. 26, 2025, when it hit $21.50. --Up 20.19% at today's intraday high; largest intraday percent increase since March 1, 2024, when it rose as much as 20.23%","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"BK4139":"生物科技","BK4007":"制药","BK4539":"次新股","LENZ":"Therapeutics","SYRE":"SPYRE THERAPEUTICS INC"},"translate_title":"Spyre Therapeutics上涨超过19%，有望创2023年11月以来最大百分比涨幅——Data Talk","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"LENZ":1.5,"SYRE":1},"content_text":"Spyre Therapeutics, Inc (SYRE) is currently at $21.14, up $3.46 or 19.54% \n\n\n \n\n\n     --Would be highest close since Feb. 24, 2025, when it closed at $21.26 \n\n\n     --On pace for largest percent increase since Nov. 28, 2023, when it rose 20.73% \n\n\n     --Currently up three of the past four days \n\n\n     --Currently up two consecutive days; up 31.93% over this period \n\n\n     --Best two-day stretch since the two days ending June 23, 2023, when it rose 275.94% \n\n\n     --Up 26.1% month-to-date \n\n\n     --Down 9.21% year-to-date; on pace for worst year since 2022, when it fell 90.53% \n\n\n     --Down 92.95% from its all-time closing high of $299.75 on April 8, 2016 \n\n\n     --Down 22.35% from 52 weeks ago (Oct. 10, 2024), when it closed at $27.22 \n\n\n     --Down 46.6% from its 52-week closing high of $39.58 on Nov. 8, 2024 \n\n\n     --Up 79.11% from its 52-week closing low of $11.80 on April 8, 2025 \n\n\n     --Traded as high as $21.25; highest intraday level since Feb. 26, 2025, when it hit $21.50 \n\n\n     --Up 20.19% at today's intraday high; largest intraday percent increase since March 1, 2024, when it rose as much as 20.23% \n\n\n \n\n\n     All data as of 1:33:51 PM ET \n\n\n \n\n\n     Source: Dow Jones Market Data, FactSet \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  October 09, 2025 13:37 ET (17:37 GMT)\n\n\n  Copyright (c) 2025 Dow Jones & Company, Inc.","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"","news_rank":0,"symbols":[],"gpt_button":0,"need_auth":true,"code":"91000000","status":"200"}}}