Positive Results from Phase 3 OptiTROP-Lung04 Trial of Sacituzumab Tirumotecan Presented at ESMO Presidential Symposium and Simultaneously Published in NEJM

prnewswire

2025/10/20

CHENGDU, China, Oct. 20, 2025 /PRNewswire/ -- Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (the "Company") announced that at the 2025 European Society for Medical Oncology (ESMO) Congress held in Berlin, Germany, results from a Phase 3 OptiTROP-Lung04 trial of the Company's trophoblast cell-surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC) sacituzumab tirumotecan (sac-TMT) in EGFR-mutated non-small cell lung cancer (NSCLC) following progression on epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) was presented as an oral report by Professor Li Zhang from Sun Yat-sen University Cancer Center (Presentation # LBA5, Presidential Symposium II) and were simultaneously published in the New England Journal of Medicine (Impact Factor = 78.5).

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(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)

(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)

(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)

(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)

(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)

(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)

(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)

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(the \"Company\") announced that at the 2025 European Society for Medical Oncology (ESMO) Congress held in Berlin, Germany, results from a Phase 3 OptiTROP-Lung04 trial of the Company's trophoblast cell-surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC) sacituzumab tirumotecan (sac-TMT)  in EGFR-mutated non-small cell lung cancer (NSCLC) following progression on epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) was presented as an oral report by Professor Li Zhang from Sun Yat-sen University Cancer Center (Presentation # LBA5, Presidential Symposium II) and were simultaneously published in the <i><a href=\"https://laohu8.com/S/NEWEN\">New England</a> Journal of Medicine</i> (Impact Factor = 78.5).</p>\n<div>\n<span>\nContinue Reading\n                  <br/>\n<i></i>\n</span>\n</div>\n<div>\n<div>\n<div>\n<div>\n</div>\n<div>\n<div>\n<div>\n<div></div>\n</div>\n<div></div>\n<div></div>\n<div></div>\n<figure>\n<div>\n<img itemprop=\"contentUrl\" loading=\"lazy\" rel=\"newsImage\" title=\"(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\"/>\n<span aria-hidden=\"true\"></span>\n</div>\n<figcaption>\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\r\n      </figcaption>\n</figure>\n</div>\n<div></div>\n<figure>\n<div>\n<img itemprop=\"contentUrl\" loading=\"lazy\" rel=\"newsImage\" title=\"(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\"/>\n<span aria-hidden=\"true\"></span>\n</div>\n<figcaption>\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\r\n      </figcaption>\n</figure>\n</div>\n<div></div>\n<figure>\n<div>\n<img itemprop=\"contentUrl\" loading=\"lazy\" rel=\"newsImage\" title=\"(PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\"/>\n<span aria-hidden=\"true\"></span>\n</div>\n<figcaption>\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\r\n      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(the \"Company\") announced that at the 2025 European Society for Medical Oncology (ESMO) Congress held in Berlin, Germany, results from a Phase 3 OptiTROP-Lung04 trial of the Company's trophoblast cell-surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC) sacituzumab tirumotecan (sac-TMT)  in EGFR-mutated non-small cell lung cancer (NSCLC) following progression on epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) was presented as an oral report by Professor Li Zhang from Sun Yat-sen University Cancer Center (Presentation # LBA5, Presidential Symposium II) and were simultaneously published in the New England Journal of Medicine (Impact Factor = 78.5).\n\n\nContinue Reading\n                  \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\r\n      \n\n\n\n\n\n\n\n\n\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\r\n      \n\n\n\n\n\n\n\n\n\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\r\n      \n\n\n\n\n\n\n\n\n\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\r\n      \n\n\n\n\n\n\n\n\n\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\r\n      \n\n\n\n\n\n\n\n\n\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)\r\n      \n\n\n\n\n\n\n\n\n\r\n        (PRNewsfoto/Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.)","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"dataReport","news_rank":0,"symbols":[],"gpt_button":0,"need_auth":false,"code":"91000000","status":"200"}}}