U.S. Small Caps End Mixed As Sionna Therapeutics Leads, OBOOK Holdings Lags

Dow Jones
10/22

This article was automatically generated using Dow Jones technology.

Shares of small-cap companies were mixed Tuesday, as the Russell 2000 Index dropped 0.5%, while the S&P Small Cap 600 Index was up 0.3%.

Among companies with a market value of $1 billion to $6.7 billion, OBOOK Holdings Inc. was the biggest laggard during the session, dropping 32%, followed by shares of Critical Metals Corp., which dropped 17%. Shares of USA Rare Earth Inc. dropped 15%, Eightco Holdings Inc. shares tumbled 15%, and Churchill Capital Corp. X Cl A plunged 13%.

Sionna Therapeutics Inc. was the best performer, surging 32%, followed by Falcon's Beyond Global Inc., which jumped 20%. Six Flags Entertainment Corp. shares surged 18%, Nuvation Bio Inc. jumped 14%, and shares of Vicor Corp. surged 13%.

Major stock indexes in the U.S. closed mixed Tuesday with the Nasdaq Composite Index falling 0.2%. Meanwhile, the S&P 500 Index was flat, and the Dow Jones Industrial Average added 0.5%.

Data source: Dow Jones Market Data, FactSet

 

(END) Dow Jones Newswires

October 21, 2025 16:20 ET (20:20 GMT)

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