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With U.S. stock markets set to open in two hours, Medpace Holdings Inc. (MEDP) was up 18.9% in pre-market trading, and D-Wave Quantum Inc. (QBTS) was up 12.9%.

IonQ Inc. $(IONQ)$, QuantumScape Corp. Cl A $(QS)$, and Rigetti Computing Inc. (RGTI) were all posting gains of at least 9%. In early trading, Molina Healthcare Inc. (MOH) and Centene Corp. $(CNC)$ had posted declines, falling 18.0% and 7.3%, respectively.

Meanwhile S&P 500 futures were down 0.04%, with futures for the Dow Jones Industrial Average falling 0.14%. The Cboe Volatility Index futures were up 1.57%.

In commodities news, Brent crude oil futures were up 5.51%, and gold futures were up 1.57%. Bitcoin was up 1.59% to $109,572.

The 10-Year Treasury yield rose to 3.993%.

In the previous regular trading session, the S&P 500 and the Dow were down 0.53% and 0.71%, respectively. Stocks in Asia were mixed overnight, with Japan's NIKKEI 225 Index down 1.35% and China's Shanghai Composite Index up 0.22%.

In afternoon trading, stocks in Europe are up, with the STOXX Europe 600 Index increasing 0.34% and the FTSE 100 Index climbing 0.64% from the previous close.

U.S. stock markets open for trading at 9:30 a.m. ET.

Data source: Dow Jones Market Data, FactSet. Data compiled October 23, 2025.

This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow Jones Newswires and The Wall Street Journal.

(END) Dow Jones Newswires

October 23, 2025 07:31 ET (11:31 GMT)

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