Summit Therapeutics Inc. has announced it has raised approximately $500 million through a private placement of about 26.68 million shares of its common stock at $18.74 per share. The proceeds will be used to advance the clinical development of ivonescimab, as well as for working capital and general corporate purposes. Company insiders, including Co-CEOs Robert W. Duggan and Dr. Mahkam Zanganeh, along with other executives and employees, invested a combined $272 million. Akeso, Inc., whose CEO Dr. Yu (Michelle) Xia is also a Summit board member, participated with a $10 million investment. The remaining $218 million was raised from multiple leading biopharma institutional and individual investors. Summit has agreed to file a registration statement with the SEC to register the resale of the shares.