Monte Rosa Therapeutics Unveils Preclinical Data on MRT-6160 for Autoimmune Diseases

Reuters
10/24
<a href="https://laohu8.com/S/GLUE">Monte Rosa Therapeutics</a> Unveils Preclinical Data on MRT-6160 for Autoimmune Diseases

Monte Rosa Therapeutics Inc. announced that it will present new preclinical data on MRT-6160, a VAV1-directed molecular glue degrader, at ACR Convergence 2025, held October 24-29 in Chicago, IL. The data will be presented in a poster session on October 26 at 10:30 am CDT. Preclinical results demonstrate that MRT-6160 inhibited disease pathology, including proteinuria, lymphadenopathy, skin lesion formation, autoantibody production, and organomegaly, in a spontaneous autoimmune disease mouse model. The findings support the potential of MRT-6160 to address multiple rheumatic autoimmune and inflammatory diseases, such as Sjögren's disease, systemic lupus erythematosus, and rheumatoid arthritis. According to the company, MRT-6160 attenuated T and B cell effector functions and reduced disease progression in preclinical studies. Further development toward Phase 2 clinical studies is underway.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Monte Rosa Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9551469-en) on October 24, 2025, and is solely responsible for the information contained therein.

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