Singapore shares ended in red Wednesday as markets parsed the latest macro data and closely followed US President Donald Trump's final leg of his Asia trip and upcoming meeting with Chinese counterpart Xi Jinping.

The Straits Times Index (STI), a key benchmark for the Singapore Exchange, ranged between 4,434.14 and 4,452.64 throughout the day. It ended the session at 4,440.210, down 10.15 points or 0.2% compared to Tuesday's close.

Data from Singapore's Department of Statistics showed a rise in the city-state's manufactured products and domestic supply indices. Singapore's Manufactured Products Price Index rose 7.3% year over year in September, extending the 6% increase in the preceding month, while the Domestic Supply Price Index rose 3.7% in September, following a 1.1% increase in August.

Meanwhile, import and export prices fell during the month. Singapore's Import Price Index fell 0.6% year on year in September, extending the 3.8% decrease in the preceding month, while the Export Price Index also fell 3.3% year on year in September, extending the 5.4% slump in the preceding month.

In company news, shares of LHN (SGX:41O, HKG:1730) were down 4% in Singapore. The company's Coliwoo unit launched its initial public offering in Singapore, seeking to raise SG$48.2 million.

The firm also said a planned property acquisition in Singapore had been called off after a court order barred the seller and one of the joint venture partners from disposing of the property due to a family dispute.

Meta Health (SGX:5DX) shares were down 17% as the company said its board plans to hire CLA Global TS to replace its long-time auditor Foo Kon Tan.