Bio-Techne Corporation, in collaboration with Nucleai, has announced the presentation of pivotal data from the SECOMBIT clinical trial at the upcoming Society for Immunotherapy of Cancer $(SITC)$ 2025 Annual Meeting. The study, selected as one of the top 150 abstracts out of over 1,200 submissions, highlights the use of Bio-Techne's spatial biology technology and Nucleai's AI-powered multimodal platform to identify predictive biomarkers in melanoma patients treated with immunotherapy and targeted therapies. Researchers used the COMET™ platform and a 28-plex multiplex immunofluorescence panel to profile 42 pre-treatment biopsies from metastatic melanoma patients. The analysis revealed immune cell interactions correlated with clinical outcomes such as progression-free and overall survival across three different treatment arms. These results will be presented at SITC 2025, with visual data from the study to be featured in Poster #528.