Vyne Therapeutics Inc. reported a net loss of $7.3 million, or $0.17 per share, for the third quarter ended September 30, 2025, compared to a net loss of $12.2 million, or $0.29 per share, for the same period in 2024. Research and development expenses decreased by 48.7% to $5.3 million, primarily due to lower expenses for repibresib and VYN202 following the termination of a Phase 2b trial in nonsegmental vitiligo and reduced clinical expenses, partially offset by a $1.0 million milestone payment for VYN202. General and administrative expenses were $2.7 million, down 8.7% from the prior year. The company reported a cash runway into the first half of 2027, citing previously announced cost reductions. Vyne is continuing a 12-week non-clinical toxicology study for VYN202 and is progressing with a strategic review to evaluate options for maximizing shareholder value, including pipeline opportunities and broader strategic alternatives.