Wall Street's main indexes extended losses to a second session on Friday, and were set for weekly declines, as concerns about the economy and sky-high valuations in the technology sector soured sentiment. .N

At 10:30 EST, the Dow Jones Industrial Average .DJI was down 0.18% at 46,825.67. The S&P 500 .SPX was down 0.59% at 6,680.42, and the Nasdaq Composite .IXIC was down 1.08% at 22,804.17.

The top three S&P 500 .PG.INX percentage gainers:

** Expedia Group Inc EXPE.OQ, up 16.7% ** Akamai Technologies Inc AKAM.OQ, up 11.2% ** Monster Beverage Corp MNST.OQ, up 7.8%

The top three S&P 500 .PL.INX percentage losers:

** Block Inc XYZ.N, down 10.1% ** Microchip Technology Inc MCHP.OQ, down 9.8% ** Take-Two Interactive Software Inc TTWO.OQ, down 8.4%

The top three NYSE .PG.N percentage gainers:

** Holley Inc HLLY.N, up 35.7% ** Globus Medical Inc GMED.N, up 31.5% ** Eastman Kodak Co KODK.N, up 24.1%

The top three NYSE .PL.N percentage losers:

** DoubleVerify Holdings Inc DV.N, down 21.1% ** Ginkgo Bioworks Holdings Inc DNA.N, down 18.0% ** Karman Holdings Inc KRMN.N, down 17.3%

The top three Nasdaq .PG.O percentage gainers:

** BIO-Key International Inc BKYI.OQ, up 82.8% ** Motorsport Games Inc MSGM.OQ, up 79.5% ** Gulf Island Fabrication Inc GIFI.OQ, up 49.4%

The top three Nasdaq .PL.O percentage losers:

** Davis Commodities Ltd DTCK.OQ, down 65.6% ** Eledon Pharmaceuticals Inc ELDN.OQ, down 59.3% ** Treace Medical Concepts Inc TMCI.OQ, down 43.8%

** Novo Nordisk A/S NVO.N: BUZZ - Edges down on weight-loss pricing deal in U.S. nL8N3WJ0DB

** Tesla Inc TSLA.O: BUZZ - Down after shareholders approve CEO Elon Musk's pay plan nL4N3WJ1D2

** Block Inc XYZ.N: BUZZ - Shares fall as Q3 profit misses estimates nL4N3WJ0S1

** Newmont Corp NEM.N: ** Sibanye Stillwater Ltd SBSW.N: ** Gold Fields Ltd GFI.N: ** Kinross Gold Corp KGC.N:

BUZZ - Gold miners gain as bullion rises on US rate-cut hopes, government shutdown woes nL4N3WJ0SQ

** Peloton Interactive Inc PTON.O: BUZZ - Jumps after quarterly revenue beats estimates nL6N3WI178

** Trade Desk Inc TTD.O: BUZZ - Rises after upbeat fourth-quarter revenue forecast nL6N3WJ0JV

** Hecla Mining Co HL.N: ** Coeur Mining Inc CDE.N: ** Wheaton Precious Metals Corp WPM.N: ** Abrdn Physical Silver Shares ETF SIVR.N:

BUZZ - Silver miners gain on US Fed rate cut optimism nL4N3WJ0V2

** 10x Genomics Inc TXG.O: BUZZ - Jumps after forecasting Q4 revenue above estimates nL4N3WJ0V8

** Hims & Hers Health Inc HIMS.N: BUZZ - Falls after Novo, Lilly strike deal with White House for weight-loss drugs nL6N3WJ0M1

** Airbnb Inc ABNB.O: BUZZ - Rises on upbeat fourth-quarter revenue forecast nL4N3WJ0VK

** Fluor Corp FLR.N: BUZZ - Rises on Q3 profit beat nL6N3WJ0ML

** Opendoor Technologies Inc OPEN.O: BUZZ - Tumbles after Q3 report, $1.2 bln direct stock offering nL6N3WJ0SW

** Intellia Therapeutics Inc NTLA.O: BUZZ - Falls after US FDA halts key heart disease trials following patient death nL4N3WJ0Y8

** Sandisk LLC SNDK.O: BUZZ - Rises on Q1 revenue beat nL6N3WJ0NC

** Affirm Holdings Inc AFRM.O: BUZZ - Surges after Q1 revenue beat, strong GMV projection nL6N3WJ0NO

** Constellation Energy Corp CEG.O: BUZZ - Falls on third-quarter profit miss nL4N3WJ10X

** Grindr Inc GRND.N: BUZZ - Jumps as Q3 results beat expectations nL6N3WJ0OG

** AirSculpt Technologies Inc AIRS.O: BUZZ - Sinks after Q3 revenue miss nL6N3WJ0O5

** Cummins Inc CMI.N: BUZZ - Brokerages lift Cummins PT as quarterly results tops estimates nL4N3WJ121

** NuScale Power Corp SMR.N: BUZZ - Falls after Q3 revenue miss nL6N3WJ0OV

** Microchip Technology Inc MCHP.O: BUZZ - Falls after downbeat Q3 net sales forecast nL6N3WJ0O9

** Monster Beverage Corp MNST.O: BUZZ - Rises after Q3 results beat nL4N3WJ133

** Organon & Co OGN.N: BUZZ - Rises after agreeing to sell postpartum bleeding device to Laborie for up to $465 mln nL4N3WJ137

** Voyager Technologies Inc VOYG.N: BUZZ - Descends again after boosted $435 mln convertible bonds sale​ nL6N3WJ0P2

** MP Materials Corp MP.N: BUZZ - Falls on wider third-quarter loss nL4N3WJ127

** ANI Pharmaceuticals Inc ANIP.O: BUZZ - Rises on Q3 results beat, FY revenue forecast raise nL6N3WJ0PM

** KKR & Co Inc KKR.N: BUZZ - Climbs after Q3 profit beat nL6N3WJ0QE

** Fulgent Genetics Inc FLGT.O: BUZZ - Rises after FY revenue forecast raise, Q3 revenue beat nL6N3WJ0Q5

** CNH Industrial NV CNH.N: BUZZ - Slides after lowering FY profit forecast nL4N3WJ0ZD

** Wendy's Co WEN.O: BUZZ - Up after Q3 profit beat nL6N3WJ0P5

** Leidos Holdings Inc LDOS.N: BUZZ - JP Morgan lifts Leidos PT on defense-led growth nL4N3WJ14J

** Enbridge Inc ENB.N: BUZZ - Falls after Q3 profit miss nL4N3WJ155

** Rhythm Pharmaceuticals Inc RYTM.O: BUZZ - Falls after US FDA delays decision on drug for brain damage-related obesity nL4N3WJ140

** Universal Display Corp OLED.O: BUZZ - Falls after Q3 revenue miss nL6N3WJ0QM

** Akamai Technologies Inc AKAM.O: BUZZ - Shares hit 3-month high on upbeat Q4 forecast, strong Q3 results nL4N3WJ1DV

** nLIGHT Inc LASR.O: BUZZ - Rises after Q3 revenue beat nL6N3WJ0QT

** Globus Medical Inc GMED.N: BUZZ - Rises after Q3 results beat nL6N3WJ0R3

** Archer Aviation Inc ACHR.N: BUZZ - Falls after announcing stock sale, Q3 results nL4N3WJ13M

** Taskus Inc TASK.O: BUZZ - Rises after Q3 earnings beat nL6N3WJ0RJ

** DraftKings Inc DKNG.O: BUZZ - Drops as Q3 revenue falls short of estimates nL6N3WJ0RG

** JFrog Ltd FROG.O: BUZZ - Shares jump 27% on Q3 results beat nL6N3WJ0RT

** MiNK Therapeutics Inc INKT.O: BUZZ - Rises after data shows long-lasting remissions in tough cancers nL4N3WJ19E

** Red Rock Resorts Inc RRR.O: BUZZ - Rises on S&P SmallCap inclusion nL6N3WJ0SD

** Gulf Island Fabrication Inc GIFI.O: BUZZ - Rises on $192 million takeover by IES Holdings nL6N3WJ0S8

** Celanese Corp CE.N: BUZZ - Jumps after Q3 profit beats estimates nL4N3WJ1DI

** Solventum Corp SOLV.N: BUZZ - Up after raising annual profit forecast nL6N3WJ0M9

** Haemonetics Corp HAE.N: BUZZ - Rises after BofA upgrades to "neutral" on prudent growth forecast nL6N3WJ0TQ

(Compiled by Rajarshi Roy and Arnav Mishra)

((Rajarshi.Roy@thomsonreuters.com))