Arcturus Therapeutics Holdings Inc. reported a net loss of $13.5 million, or $0.49 per diluted share, for the third quarter ended September 30, 2025, compared to a net loss of $6.9 million, or $0.26 per diluted share, for the same period in 2024. For the first nine months of 2025, the net loss was $36.7 million, or $1.35 per diluted share, down from $50.9 million, or $1.89 per diluted share, for the same period in 2024. Revenue for the third quarter was $17.2 million, a decrease of $24.5 million from the previous year, and revenue for the nine-month period was $74.8 million, a decline of $54.7 million compared to 2024. Cash, cash equivalents, and restricted cash totaled $237.3 million as of September 30, 2025. The company announced additional cost reductions planned for the fourth quarter to extend its cash runway into 2028. Arcturus also reported progress in its clinical pipeline, including interim Phase 2 data for its cystic fibrosis program and ongoing development of its OTC deficiency program. The U.S. BLA filing for KOSTAIVE has been delayed indefinitely due to changes in FDA regulatory requirements.