Applied Therapeutics Inc. reported its financial results for the third quarter ended September 30, 2025. The company announced cash and cash equivalents of $11.9 million as of September 30, 2025, compared to $79.4 million at December 31, 2024. Applied Therapeutics provided updates on its regulatory strategy for govorestat, including a completed meeting with the FDA regarding a potential NDA submission for the treatment of CMT-SORD and plans to submit a meeting request for further discussion on a potential Phase 3 trial. A meeting with the FDA is also scheduled in the fourth quarter of 2025 to discuss govorestat for Classic Galactosemia. Additionally, new data on govorestat for PMM2-CDG was published and presented at the 2025 ASHG Annual Meeting. The company also announced a leadership transition, with John Johnson stepping down as Executive Chairman and director for personal reasons.