Arbutus Biopharma Unveils Progress Toward Functional Cure for Chronic Hepatitis B

Reuters

2025/11/13

<a href="https://laohu8.com/S/ABUS">Arbutus Biopharma</a> Unveils Progress Toward Functional Cure for Chronic Hepatitis B

Arbutus Biopharma Corp. has provided an update on its ongoing efforts to develop treatments for chronic hepatitis B (cHBV). The company highlighted progress with its lead siRNA therapeutic candidate, imdusiran, which demonstrated durable viral suppression and multiple functional cures in a Phase 2a clinical trial. The data showed meaningful reductions in both HBsAg and HBV DNA, with some patients able to discontinue therapy. Imdusiran was generally safe and well tolerated in the studies presented. Arbutus also reported a strong financial position, with cash and cash equivalents totaling $94 million as of September 30, 2025. The company is evaluating development plans for a Phase 2b clinical trial of imdusiran and continues to advance its immunotherapy program, including the oral PD-L1 inhibitor AB-101. You can access the full presentation through the link below.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Arbutus Biopharma Corp. published the original content used to generate this news brief on November 13, 2025, and is solely responsible for the information contained therein.

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The company highlighted progress with its lead siRNA therapeutic candidate, imdusiran, which demonstrated durable viral suppression and multiple functional cures in a Phase 2a clinical trial. The data showed meaningful reductions in both HBsAg and HBV DNA, with some patients able to discontinue therapy. Imdusiran was generally safe and well tolerated in the studies presented. Arbutus also reported a strong financial position, with cash and cash equivalents totaling $94 million as of September 30, 2025. The company is evaluating development plans for a Phase 2b clinical trial of imdusiran and continues to advance its immunotherapy program, including the oral PD-L1 inhibitor AB-101. 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Arbutus Biopharma Corp. published the original content used to generate this news brief on November 13, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"ABUS","symbol_name":"Arbutus Biopharma Corporation","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251113:nNDLc7lsnt:1","article_id":"2583672355","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2583672355","pubTimestamp":1763037474,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Arbutus Biopharma Corp. has provided an update on its ongoing efforts to develop treatments for chronic hepatitis B . 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